Treatment With Simvastatin Suppresses the Development of Experimental Abdominal Aortic Aneurysms in Normal and Hypercholesterolemic Mice

OBJECTIVE: To determine if treatment with hydroxymethylglutaryl-coenzyme A reductase inhibitors (statins) can influence the development of experimental abdominal aortic aneurysms (AAAs). SUMMARY BACKGROUND DATA: AAAs are associated with atherosclerosis, chronic inflammation, and matrix metalloprotei...

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Bibliografiska uppgifter
Huvudupphovsmän: Steinmetz, Eric F., Buckley, Celine, Shames, Murray L., Ennis, Terri L., Vanvickle-Chavez, Sarah J., Mao, Dongli, Goeddel, Lee A., Hawkins, Cherady J., Thompson, Robert W.
Materialtyp: Artigo
Språk:Inglês
Publicerad: 2005
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Original Articles
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC1356851/
https://ncbi.nlm.nih.gov/pubmed/15621996
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/01.sla.0000150258.36236.e0
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