Mammalian Copper Chaperone Cox17p Has an Essential Role in Activation of Cytochrome c Oxidase and Embryonic Development

Cox17p is essential for the assembly of functional cytochrome c oxidase (CCO) and for delivery of copper ions to the mitochondrion for insertion into the enzyme in yeast. Although this small protein has already been cloned or purified from humans, mice, and pigs, the function of Cox17p in the mammal...

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Autori principali: Takahashi, Yoshinori, Kako, Koichiro, Kashiwabara, Shin-ichi, Takehara, Akio, Inada, Yoshiko, Arai, Hidenori, Nakada, Kazuto, Kodama, Hiroko, Hayashi, Jun-ichi, Baba, Tadashi, Munekata, Eisuke
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Microbiology 2002
Soggetti:
Mammalian Genetic Models with Minimal or Complex Phenotypes
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC135665/
https://ncbi.nlm.nih.gov/pubmed/12370308
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.22.21.7614-7621.2002
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