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Gamma Interferon Triggers Interaction between ICSBP (IRF-8) and TEL, Recruiting the Histone Deacetylase HDAC3 to the Interferon-Responsive Element

ICSBP (IRF-8) is a transcription factor of the IRF family expressed only in the immune system. It is induced in macrophages by gamma interferon (IFN-γ) and contributes to macrophage functions. By interacting with Ets family protein PU.1, ICSBP binds to the IRF/Ets composite element and stimulates tr...

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Published in:Mol Cell Biol
Main Authors: Kuwata, Takeshi, Gongora, Celine, Kanno, Yuka, Sakaguchi, Kazuyasu, Tamura, Tomohiko, Kanno, Tomohiko, Basrur, Venkatesha, Martinez, Robert, Appella, Ettore, Golub, Todd, Ozato, Keiko
Format: Artigo
Language:Inglês
Published: Taylor & Francis 2002
Subjects:
Transcriptional Regulation
Online Access:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC135656/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/12370291/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/MCB.22.21.7439-7448.2002
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