Early Postnatal Death and Motor Disorders in Mice Congenitally Deficient in Calnexin Expression

Calnexin is a ubiquitously expressed type I membrane protein which is exclusively localized in the endoplasmic reticulum (ER). In mammalian cells, calnexin functions as a chaperone molecule and plays a key role in glycoprotein folding and quality control within the ER by interacting with folding int...

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Autores principales: Denzel, Angela, Molinari, Maurizio, Trigueros, Cesar, Martin, Joanne E., Velmurgan, Shanti, Brown, Sue, Stamp, Gordon, Owen, Michael J.
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society for Microbiology 2002
Materias:
Mammalian Genetic Models with Minimal or Complex Phenotypes
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC135653/
https://ncbi.nlm.nih.gov/pubmed/12370287
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.22.21.7398-7404.2002
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