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Distinct modes of ATR activation after replication stress and DNA double-strand breaks in Caenorhabditis elegans
ATM and ATR are key components of the DNA damage checkpoint. ATR primarily responds to UV damage and replication stress, yet may also function with ATM in the checkpoint response to DNA double-strand breaks (DSBs), although this is less clear. Here, we show that atl-1 (Caenorhabditis elegans ATR) an...
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| Main Authors: | , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Nature Publishing Group
2005
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| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1356337/ https://ncbi.nlm.nih.gov/pubmed/16319925 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.emboj.7600896 |
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