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NGF rapidly increases membrane expression of TRPV1 heat-gated ion channels

Nociceptors, or pain-sensitive receptors, are unique among sensory receptors in that their sensitivity is increased by noxious stimulation. This process, called sensitization or hyperalgesia, is mediated by a variety of proinflammatory factors, including bradykinin, ATP and NGF, which cause sensitiz...

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Bibliographic Details
Main Authors: Zhang, Xuming, Huang, Jiehong, McNaughton, Peter A
Format: Artigo
Language:Inglês
Published: Nature Publishing Group 2005
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC1356334/
https://ncbi.nlm.nih.gov/pubmed/16319926
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.emboj.7600893
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