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The Requirement for ATP Hydrolysis by Saccharomyces cerevisiae Rad51 Is Bypassed by Mating-Type Heterozygosity or RAD54 in High Copy

Rad51 can promote extensive strand exchange in vitro in the absence of ATP hydrolysis, and the Rad51-K191R mutant protein, which can bind but poorly hydrolyze ATP, also promotes strand exchange. A haploid strain expressing the rad51-K191R allele showed an equivalent sensitivity at low doses of ioniz...

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Detalles Bibliográficos
Main Authors: Morgan, Elizabeth A., Shah, Naseem, Symington, Lorraine S.
Formato: Artigo
Idioma:Inglês
Publicado: American Society for Microbiology 2002
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC135622/
https://ncbi.nlm.nih.gov/pubmed/12192033
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.22.18.6336-6343.2002
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