The Regulation of Hypoxic Genes by Calcium Involves c-Jun/AP-1, Which Cooperates with Hypoxia-Inducible Factor 1 in Response to Hypoxia

Hypoxia causes the accumulation of the transcription factor hypoxia-inducible factor 1 (HIF-1), culminating in the expression of hypoxia-inducible genes such as those for vascular endothelial growth factor (VEGF) and NDRG-1/Cap43. Previously, we have demonstrated that intracellular calcium (Ca(2+))...

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Bibliographic Details
Main Authors: Salnikow, Konstantin, Kluz, Thomas, Costa, Max, Piquemal, David, Demidenko, Zoya N., Xie, Keping, Blagosklonny, Mikhail V.
Format: Artigo
Language:Inglês
Published: American Society for Microbiology 2002
Subjects:
Cell Growth and Development
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC135615/
https://ncbi.nlm.nih.gov/pubmed/11865053
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.22.6.1734-1741.2002
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