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Computational Analysis and Prediction of the Binding Motif and Protein Interacting Partners of the Abl SH3 Domain

Protein-protein interactions, particularly weak and transient ones, are often mediated by peptide recognition domains, such as Src Homology 2 and 3 (SH2 and SH3) domains, which bind to specific sequence and structural motifs. It is important but challenging to determine the binding specificity of th...

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Detalhes bibliográficos
Main Authors: Hou, Tingjun, Chen, Ken, McLaughlin, William A, Lu, Benzhuo, Wang, Wei
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2006
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1356089/
https://ncbi.nlm.nih.gov/pubmed/16446784
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pcbi.0020001
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