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Ral-GTPase Influences the Regulation of the Readily Releasable Pool of Synaptic Vesicles

The Ral proteins are members of the Ras superfamily of GTPases. Because they reside in synaptic vesicles, we used transgenic mice expressing a dominant inhibitory form of Ral to investigate the role of Ral in neurosecretion. Using a synaptosomal secretion assay, we found that while K(+)-evoked secre...

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Autores principales: Polzin, Atsuko, Shipitsin, Michail, Goi, Takanori, Feig, Larry A., Turner, Timothy J.
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society for Microbiology 2002
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC135608/
https://ncbi.nlm.nih.gov/pubmed/11865051
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.22.6.1714-1722.2002
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