Promoter Scanning for Transcription Inhibition with DNA-Binding Polyamides

When targeted to sequences adjacent to a TATA element, pyrrole-imidazole (Py-Im) polyamides inhibit the DNA binding activity of TATA box binding protein (TBP) and basal transcription by RNA polymerase II. In the present study, we scanned the human immunodeficiency virus type 1 promoter for polyamide...

Celý popis

Uloženo v:
Podrobná bibliografie
Hlavní autoři: Ehley, Jennifer A., Melander, Christian, Herman, David, Baird, Eldon E., Ferguson, Heather A., Goodrich, James A., Dervan, Peter B., Gottesfeld, Joel M.
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Microbiology 2002
Témata:
Transcriptional Regulation
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC135605/
https://ncbi.nlm.nih.gov/pubmed/11865052
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.22.6.1723-1733.2002
Tagy: Přidat tag
Žádné tagy, Buďte první, kdo otaguje tento záznam!

Podobné jednotky