Promoter Scanning for Transcription Inhibition with DNA-Binding Polyamides

When targeted to sequences adjacent to a TATA element, pyrrole-imidazole (Py-Im) polyamides inhibit the DNA binding activity of TATA box binding protein (TBP) and basal transcription by RNA polymerase II. In the present study, we scanned the human immunodeficiency virus type 1 promoter for polyamide...

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Detalhes bibliográficos

Publicado no:	Mol Cell Biol
Principais autores:	Ehley, Jennifer A., Melander, Christian, Herman, David, Baird, Eldon E., Ferguson, Heather A., Goodrich, James A., Dervan, Peter B., Gottesfeld, Joel M.
Formato:	Artigo
Idioma:	Inglês
Publicado em:	Taylor & Francis 2002
Assuntos:	Transcriptional Regulation
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC135605/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11865052/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/MCB.22.6.1723-1733.2002
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