Mutants of Streptomyces clavuligerus with Disruptions in Different Genes for Clavulanic Acid Biosynthesis Produce Large Amounts of Holomycin: Possible Cross-Regulation of Two Unrelated Secondary Metabolic Pathways

A Streptomyces clavuligerus ccaR::aph strain, which has a disruption in the regulatory gene ccaR, does not produce cephamycin C or clavulanic acid, but does produce a bioactive compound that was identified as holomycin by high-performance liquid chromatography (HPLC) and infrared and mass spectromet...

Ful tanımlama

Kaydedildi:
Detaylı Bibliyografya
Asıl Yazarlar: de la Fuente, Alvaro, Lorenzana, Luis M., Martín, Juan F., Liras, Paloma
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: American Society for Microbiology 2002
Konular:
Physiology and Metabolism
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC135446/
https://ncbi.nlm.nih.gov/pubmed/12426344
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JB.184.23.6559-6565.2002
Etiketler: Etiketle
Etiket eklenmemiş, İlk siz ekleyin!

Benzer Materyaller