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The First Archaeal ATP-Dependent Glucokinase, from the Hyperthermophilic Crenarchaeon Aeropyrum pernix, Represents a Monomeric, Extremely Thermophilic ROK Glucokinase with Broad Hexose Specificity

An ATP-dependent glucokinase of the hyperthermophilic aerobic crenarchaeon Aeropyrum pernix was purified 230-fold to homogeneity. The enzyme is a monomeric protein with an apparent molecular mass of about 36 kDa. The apparent K(m) values for ATP and glucose (at 90°C and pH 6.2) were 0.42 and 0.044 m...

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Detalhes bibliográficos
Main Authors: Hansen, Thomas, Reichstein, Bianca, Schmid, Roland, Schönheit, Peter
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2002
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC135380/
https://ncbi.nlm.nih.gov/pubmed/12374829
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JB.184.21.5955-5965.2002
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