Formation of Protoanemonin from 2-Chloro-cis,cis-Muconate by the Combined Action of Muconate Cycloisomerase and Muconolactone Isomerase

Muconate cycloisomerases are known to catalyze the reversible conversion of 2-chloro-cis,cis-muconate by 1,4- and 3,6-cycloisomerization into (4S)-(+)-2-chloro- and (4R/5S)-(+)-5-chloromuconolactone. 2-Chloromuconolactone is transformed by muconolactone isomerase with concomitant dechlorination and...

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Bibliografiske detaljer
Main Authors: Skiba, Anke, Hecht, Volker, Pieper, Dietmar Helmut
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology 2002
Fag:
Enzymes and Proteins
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC135365/
https://ncbi.nlm.nih.gov/pubmed/12218027
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JB.184.19.5402-5409.2002
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