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Identification of a DtxR-Regulated Operon That Is Essential for Siderophore-Dependent Iron Uptake in Corynebacterium diphtheriae

The diphtheria toxin repressor (DtxR) uses Fe(2+) as a corepressor and inhibits transcription from iron-regulated promoters (IRPs) in Corynebacterium diphtheriae. A new IRP, designated IRP6, was cloned from C. diphtheriae by a SELEX-like procedure. DtxR bound to IRP6 in vitro only in the presence of...

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Detalhes bibliográficos
Main Authors: Qian, Yilei, Lee, John H., Holmes, Randall K.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2002
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC135300/
https://ncbi.nlm.nih.gov/pubmed/12169610
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JB.184.17.4846-4856.2002
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