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Membrane Protein Degradation by FtsH Can Be Initiated from Either End
FtsH, a membrane-bound metalloprotease, with cytoplasmic metalloprotease and AAA ATPase domains, degrades both soluble and integral membrane proteins in Escherichia coli. In this paper we investigated how membrane-embedded substrates are recognized by this enzyme. We showed previously that FtsH can...
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Main Authors: | , , |
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Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
American Society for Microbiology
2002
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC135282/ https://ncbi.nlm.nih.gov/pubmed/12169602 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JB.184.17.4775-4782.2002 |
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