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Membrane Protein Degradation by FtsH Can Be Initiated from Either End

FtsH, a membrane-bound metalloprotease, with cytoplasmic metalloprotease and AAA ATPase domains, degrades both soluble and integral membrane proteins in Escherichia coli. In this paper we investigated how membrane-embedded substrates are recognized by this enzyme. We showed previously that FtsH can...

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Detalhes bibliográficos
Main Authors: Chiba, Shinobu, Akiyama, Yoshinori, Ito, Koreaki
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2002
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC135282/
https://ncbi.nlm.nih.gov/pubmed/12169602
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JB.184.17.4775-4782.2002
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