From Genetic Footprinting to Antimicrobial Drug Targets: Examples in Cofactor Biosynthetic Pathways

Novel drug targets are required in order to design new defenses against antibiotic-resistant pathogens. Comparative genomics provides new opportunities for finding optimal targets among previously unexplored cellular functions, based on an understanding of related biological processes in bacterial p...

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Autors principals: Gerdes, Svetlana Y., Scholle, Michael D., D'Souza, Mark, Bernal, Axel, Baev, Mark V., Farrell, Michael, Kurnasov, Oleg V., Daugherty, Matthew D., Mseeh, Faika, Polanuyer, Boris M., Campbell, John W., Anantha, Shubha, Shatalin, Konstantin Y., Chowdhury, Shamim A. K., Fonstein, Michael Y., Osterman, Andrei L.
Format: Artigo
Idioma:Inglês
Publicat: American Society for Microbiology 2002
Matèries:
Meeting Presentations
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC135229/
https://ncbi.nlm.nih.gov/pubmed/12142426
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JB.184.16.4555-4572.2002
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