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Ephrin-As and neural activity are required for eye-specific patterning during retinogeniculate mapping

In mammals, retinal ganglion cell projections initially intermingle and then segregate into a stereotyped pattern of eye-specific layers in the dorsal lateral geniculate nucleus (dLGN). We show here that, in mice deficient for ephrin-A2, ephrin-A3, and ephrin-A5, eye-specific inputs segregate but th...

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Detalhes bibliográficos
Main Authors: Pfeiffenberger, Cory, Cutforth, Tyler, Woods, Georgia, Yamada, Jena, Renteri’a, Rene’ C., Copenhagen, David R., Flanagan, John G., Feldheim., David A.
Formato: Artigo
Idioma:Inglês
Publicado em: 2005
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1352169/
https://ncbi.nlm.nih.gov/pubmed/16025107
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nn1508
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