Enterococcus faecalis 3-Hydroxy-3-Methylglutaryl Coenzyme A Synthase, an Enzyme of Isopentenyl Diphosphate Biosynthesis

Biosynthesis of the isoprenoid precursor isopentenyl diphosphate (IPP) proceeds via two distinct pathways. Sequence comparisons and microbiological data suggest that multidrug-resistant strains of gram-positive cocci employ exclusively the mevalonate pathway for IPP biosynthesis. Bacterial mevalonat...

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Autors principals: Sutherlin, Autumn, Hedl, Matija, Sanchez-Neri, Barbara, Burgner II, John W., Stauffacher, Cynthia V., Rodwell, Victor W.
Format: Artigo
Idioma:Inglês
Publicat: American Society for Microbiology 2002
Matèries:
Enzymes and Proteins
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC135212/
https://ncbi.nlm.nih.gov/pubmed/12107122
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JB.184.15.4065-4070.2002
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