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Mutant Analysis Shows that Alanine Racemases from Pseudomonas aeruginosa and Escherichia coli Are Dimeric

Alanine racemases are ubiquitous prokaryotic enzymes providing the essential peptidoglycan precursor d-alanine. We present evidence that the enzymes from Pseudomonas aeruginosa and Escherichia coli function exclusively as homodimers. Moreover, we demonstrate that expression of a K35A Y235A double mu...

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Autores principales: Strych, Ulrich, Benedik, Michael J.
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society for Microbiology 2002
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC135199/
https://ncbi.nlm.nih.gov/pubmed/12107154
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JB.184.15.4321-4325.2002
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