Global Transcriptional Analysis of clpP Mutations of Type 2 Streptococcus pneumoniae and Their Effects on Physiology and Virulence

Streptococcus pneumoniae is an important human pathogen that contains single copies of genes encoding the ClpP and FtsH ATP-dependent proteases but lacks the Lon and HslV proteases. We constructed and characterized the phenotypes of clpP, clpC, and clpX deletion replacement mutants, which lack the C...

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Bibliographic Details
Main Authors: Robertson, Gregory T., Ng, Wai-Leung, Foley, Joseph, Gilmour, Raymond, Winkler, Malcolm E.
Format: Artigo
Language:Inglês
Published: American Society for Microbiology 2002
Subjects:
Molecular Biology of Pathogens
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC135132/
https://ncbi.nlm.nih.gov/pubmed/12057945
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JB.184.13.3508-3520.2002
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