Paracrine Modulation of Androgen Synthesis in Rat Leydig Cells by Nitric Oxide

The free radical nitric oxide (NO), generated through the oxidation of l-arginine to l-citrulline by NO synthases (NOSs), has been shown to inhibit steroidogenic pathways. NOS isoforms are known to be present in rat and human testes. Our study examined the sensitivity of Leydig cells to NO and deter...

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Bibliographic Details
Main Authors: WEISSMAN, BEN A., NIU, ENMEI, GE, RENSHAN, SOTTAS, CHANTAL M., HOLMES, MICHAEL, HUTSON, JAMES C., HARDY, MATTHEW P.
Format: Artigo
Language:Inglês
Published: 2005
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC1351298/
https://ncbi.nlm.nih.gov/pubmed/15867005
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2164/jandrol.04178
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