Innate immunity mediated by TLR9 modulates pathogenicity in an animal model of multiple sclerosis

Inflammatory diseases of the CNS, such as MS and its animal model EAE, are characterized by infiltration of activated lymphocytes and phagocytes into the CNS. Within the CNS, activation of resident cells initiates an inflammatory cascade, leading to tissue destruction, demyelination, and neurologic...

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Detalhes bibliográficos
Main Authors: Prinz, Marco, Garbe, Folker, Schmidt, Hauke, Mildner, Alexander, Gutcher, Ilona, Wolter, Karina, Piesche, Matthias, Schroers, Roland, Weiss, Elisabeth, Kirschning, Carsten J., Rochford, Christian D.P., Brück, Wolfgang, Becher, Burkhard
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Clinical Investigation 2006
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1350999/
https://ncbi.nlm.nih.gov/pubmed/16440059
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI26078
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