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Negative feedback regulation of noradrenaline release by nerve stimulation in the perfused cat's spleen: differences in potency of phenoxybenzamine in blocking the pre- and post-synaptic adrenergic receptors

1. The effects of low concentrations of phenoxybenzamine (8·8 × 10(-10) to 2·9 × 10(-7) M) on responses and on noradrenaline overflow elicited by nerve stimulation were studied in the perfused cat's spleen. 2. In the presence of 8·8 × 10(-10) M or 2·9 × 10(-9) M phenoxybenzamine there was a sig...

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Detalhes bibliográficos
Main Authors: Dubocovich, Margarita L., Langer, S. Z.
Formato: Artigo
Idioma:Inglês
Publicado em: 1974
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1350902/
https://ncbi.nlm.nih.gov/pubmed/4363457
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