Polymorphisms of Cytochrome P4501A2 and N-acetyltransferase genes, Smoking, and Risk of Pancreatic Cancer

To test the hypothesis that genetic variation in the metabolism of tobacco carcinogens, such as aromatic amines (AA) and heterocyclic amines (HCA), contributes to pancreatic cancer, we have examined genetic polymorphisms of three key enzymes, i.e. cytochrome P450 1A2 (CYP1A2) and N-acetyltransferase...

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Main Authors: Li, Donghui, Jiao, Li, Li, Yanan, Doll, Mark A., Hein, David W., Bondy, Melissa L., Evans, Douglas B., Wolff, Robert A., Lenzi, Renato, Pisters, Peter W., Abbruzzese, James L., Hassan, Manal M.
Format: Artigo
Jezik:Inglês
Izdano: 2005
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Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC1350610/
https://ncbi.nlm.nih.gov/pubmed/15987714
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/carcin/bgi171
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