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Endotoxin of Neisseria meningitidis Composed Only of Intact Lipid A: Inactivation of the Meningococcal 3-Deoxy-d-Manno-Octulosonic Acid Transferase

Lipopolysaccharide, lipooligosaccharide (LOS), or endotoxin is important in bacterial survival and the pathogenesis of gram-negative bacteria. A necessary step in endotoxin biosynthesis is 3-deoxy-d-manno-octulosonic acid (Kdo) glycosylation of lipid A, catalyzed by the Kdo transferase KdtA (WaaA)....

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Bibliografiske detaljer
Main Authors: Tzeng, Yih-Ling, Datta, Anup, Kolli, V. Kumar, Carlson, Russell W., Stephens, David S.
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology 2002
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC134985/
https://ncbi.nlm.nih.gov/pubmed/11948150
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JB.184.9.2379-2388.2002
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