A MecA Paralog, YpbH, Binds ClpC, Affecting both Competence and Sporulation

ComK, the master regulator of competence, is degraded by the general stress-related protease ClpCP but must be targeted to this protease by binding to the adapter protein MecA. The genome of Bacillus subtilis contains a paralog of mecA, ypbH. We show in the present study that YpbH, like MecA, binds...

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Bibliographic Details
Main Authors: Persuh, Marjan, Mandic-Mulec, Ines, Dubnau, David
Format: Artigo
Language:Inglês
Published: American Society for Microbiology 2002
Subjects:
Genetics and Molecular Biology
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC134970/
https://ncbi.nlm.nih.gov/pubmed/11914365
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JB.184.8.2310-2313.2002
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