Enterococcus faecalis Acetoacetyl-Coenzyme A Thiolase/3-Hydroxy-3-Methylglutaryl-Coenzyme A Reductase, a Dual-Function Protein of Isopentenyl Diphosphate Biosynthesis

Many bacteria employ the nonmevalonate pathway for synthesis of isopentenyl diphosphate, the monomer unit for isoprenoid biosynthesis. However, gram-positive cocci exclusively use the mevalonate pathway, which is essential for their growth (E. I. Wilding et al., J. Bacteriol. 182:4319-4327, 2000). E...

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Autori principali: Hedl, Matija, Sutherlin, Autumn, Wilding, E. Imogen, Mazzulla, Marie, McDevitt, Damien, Lane, Pamela, Burgner, John W., Lehnbeuter, Kevin R., Stauffacher, Cynthia V., Gwynn, Michael N., Rodwell, Victor W.
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Microbiology 2002
Soggetti:
Enzymes and Proteins
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC134966/
https://ncbi.nlm.nih.gov/pubmed/11914342
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JB.184.8.2116-2122.2002
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