Determinants of the C-Terminal Domain of the Escherichia coli RNA Polymerase α Subunit Important for Transcription at Class I Cyclic AMP Receptor Protein-Dependent Promoters

Alanine scanning of the Escherichia coli RNA polymerase α subunit C-terminal domain (αCTD) was used to identify amino acid side chains important for class I cyclic AMP receptor protein (CRP)-dependent transcription. Key residues were investigated further in vivo and in vitro. Substitutions in three...

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Detalhes bibliográficos
Main Authors: Savery, Nigel J., Lloyd, Georgina S., Busby, Stephen J. W., Thomas, Mark S., Ebright, Richard H., Gourse, Richard L.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2002
Assuntos:
Gene Regulation
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC134954/
https://ncbi.nlm.nih.gov/pubmed/11914359
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JB.184.8.2273-2280.2002
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