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Conserved Low-Affinity Nickel-Binding Amino Acids Are Essential for the Function of the Nickel Permease NixA of Helicobacter pylori

Nickel acquisition is necessary for urease activity, a major virulence factor of the human gastric pathogen Helicobacter pylori. The nickel permease NixA of H. pylori is a member of the single-component nickel-cobalt transporter family. To identify functionally relevant amino acids of NixA, single-s...

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Autori principali: Wolfram, Lutz, Bauerfeind, Peter
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Microbiology 2002
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC134868/
https://ncbi.nlm.nih.gov/pubmed/11844775
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JB.184.5.1438-1443.2002
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