The Pseudomonas aeruginosa Quorum-Sensing Molecule N-(3-Oxododecanoyl)Homoserine Lactone Contributes to Virulence and Induces Inflammation In Vivo

Pseudomonas aeruginosa has two well-characterized quorum-sensing systems, Las and Rhl. These systems are composed of LuxR-type proteins, LasR and RhlR, and two acyl homoserine lactone (AHL) synthases, LasI and RhlI. LasI catalyzes the synthesis of N-(3-oxododecanoyl)homoserine lactone (3O-C(12)-HSL)...

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Detalhes bibliográficos
Main Authors: Smith, Roger S., Harris, Sarah G., Phipps, Richard, Iglewski, Barbara
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2002
Assuntos:
Meeting Presentations
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC134808/
https://ncbi.nlm.nih.gov/pubmed/11807074
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/jb.184.4.1132-1139.2002
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