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Postsynaptic TrkB signaling has distinct roles in spine maintenance in adult visual cortex and hippocampus

In adult primary visual cortex (V1), dendritic spines are more persistent than during development. Brain-derived neurotrophic factor (BDNF) increases synaptic strength, and its levels rise during cortical development. We therefore asked whether postsynaptic BDNF signaling through its receptor TrkB r...

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Bibliografiska uppgifter
Huvudupphovsmän: Chakravarthy, Sridhara, Saiepour, M. Hadi, Bence, Matthew, Perry, Sean, Hartman, Robin, Couey, Jonathan J., Mansvelder, Huibert D., Levelt, Christiaan N.
Materialtyp: Artigo
Språk:Inglês
Publicerad: National Academy of Sciences 2006
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Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC1347973/
https://ncbi.nlm.nih.gov/pubmed/16418274
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0506305103
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