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Mutations in the GTPase Center of Escherichia coli 23S rRNA Indicate Release Factor 2-Interactive Sites

Mutations in the GTPase center of Escherichia coli 23S rRNA were characterized in vivo as UGA-specific nonsense suppressors. Some site-directed mutations did not exhibit suppressor activity and were interspersed among suppressor mutations. Our results demonstrate the involvement of the two adjacent...

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Udgivet i:J Bacteriol
Principais autores: Xu, Wenbing, Pagel, Frances T., Murgola, Emanuel J.
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology (ASM) 2002
Fag:
Structural Biology
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC134791/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11807083/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jb.184.4.1200-1203.2002
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