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SIDDBASE: a database containing the stress-induced DNA duplex destabilization (SIDD) profiles of complete microbial genomes

Prokaryotic genomic DNA is generally negatively supercoiled in vivo. Many regulatory processes, including the initiation of transcription, are known to depend on the superhelical state of the DNA substrate. The stresses induced within DNA by negative superhelicity can destabilize the DNA duplex at s...

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Autors principals: Wang, Huiquan, Kaloper, Miroslava, Benham, Craig J.
Format: Artigo
Idioma:Inglês
Publicat: Oxford University Press 2006
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC1347370/
https://ncbi.nlm.nih.gov/pubmed/16381890
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkj007
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