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Topologically Fixed SecG Is Fully Functional

It has been proposed that the bitopic membrane protein SecG undergoes topology inversion during translocation of (pre)proteins via SecYEG. Here we show that SecG covalently cross-linked to SecY cannot invert its topology while remaining fully functional in protein translocation. Our results strongly...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: van der Sluis, Eli O., van der Vries, Erhard, Berrelkamp, Greetje, Nouwen, Nico, Driessen, Arnold J. M.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: American Society for Microbiology 2006
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC1347354/
https://ncbi.nlm.nih.gov/pubmed/16428426
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JB.188.3.1188-1190.2006
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