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Topologically Fixed SecG Is Fully Functional
It has been proposed that the bitopic membrane protein SecG undergoes topology inversion during translocation of (pre)proteins via SecYEG. Here we show that SecG covalently cross-linked to SecY cannot invert its topology while remaining fully functional in protein translocation. Our results strongly...
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| Hlavní autoři: | , , , , |
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| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
American Society for Microbiology
2006
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| Témata: | |
| On-line přístup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1347354/ https://ncbi.nlm.nih.gov/pubmed/16428426 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JB.188.3.1188-1190.2006 |
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