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The Retinoblastoma Protein Binds the Promoter of the Survival Gene bcl-2 and Regulates Its Transcription in Epithelial Cells through Transcription Factor AP-2

The retinoblastoma (RB) gene product has been shown to restrict cell proliferation, promote cell differentiation, and inhibit apoptosis. Loss of RB function can induce both p53-dependent apoptosis and p53-independent apoptosis; little is known about the mechanisms of RB-regulated p53-independent apo...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Decary, Stephanie, Decesse, Julien T., Ogryzko, Vasily, Reed, John C., Naguibneva, Irina, Harel-Bellan, Annick, Cremisi, Chantal E.
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Microbiology 2002
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC134726/
https://ncbi.nlm.nih.gov/pubmed/12391156
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.22.22.7877-7888.2002
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