Infectious Molecular Clones from a Simian Immunodeficiency Virus-Infected Rapid-Progressor (RP) Macaque: Evidence of Differential Selection of RP-Specific Envelope Mutations In Vitro and In Vivo

A minor fraction of simian immunodeficiency virus (SIV)-infected macaques progress rapidly to AIDS in the absence of SIV-specific immune responses. Common mutations in conserved residues of env in three SIVsmE543-3-infected rapid-progressor (RP) macaques suggest the evolution of a common viral varia...

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Detalhes bibliográficos
Main Authors: Kuwata, Takeo, Dehghani, Houman, Brown, Charles R., Plishka, Ronald, Buckler-White, Alicia, Igarashi, Tatsuhiko, Mattapallil, Joseph, Roederer, Mario, Hirsch, Vanessa M.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2006
Assuntos:
Pathogenesis and Immunity
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1346964/
https://ncbi.nlm.nih.gov/pubmed/16415023
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.80.3.1463-1475.2006
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