Palmitoylations on Murine Coronavirus Spike Proteins Are Essential for Virion Assembly and Infectivity

Coronavirus spike (S) proteins are palmitoylated at several cysteine residues clustered near their transmembrane-spanning domains. This is achieved by cellular palmitoyl acyltransferases (PATs), which can modify newly synthesized S proteins before they are assembled into virion envelopes at the inte...

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Bibliographic Details
Main Authors: Thorp, Edward B., Boscarino, Joseph A., Logan, Hillary L., Goletz, Jeffrey T., Gallagher, Thomas M.
Format: Artigo
Language:Inglês
Published: American Society for Microbiology 2006
Subjects:
Structure and Assembly
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC1346925/
https://ncbi.nlm.nih.gov/pubmed/16415005
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.80.3.1280-1289.2006
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