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RNA Sequence and Base Pairing Effects on Insertion Editing in Trypanosoma brucei

RNA editing inserts and deletes uridylates (U's) in kinetoplastid mitochondrial pre-mRNAs by a series of enzymatic steps. Small guide RNAs (gRNAs) specify the edited sequence. Editing, though sometimes extensive, is precise. The effects of mutating pre-mRNA and gRNA sequences in, around, and up...

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Autors principals: Igo, Robert P., Lawson, Sobomabo D., Stuart, Kenneth
Format: Artigo
Idioma:Inglês
Publicat: American Society for Microbiology 2002
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC134691/
https://ncbi.nlm.nih.gov/pubmed/11839822
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