Identification of Akt Association and Oligomerization Domains of the Akt Kinase Coactivator TCL1

Serine/threonine kinase Akt/protein kinase B, the cellular homologue of the transforming viral oncogene v-Akt, plays a central role in the regulation of cell survival and proliferation. We have previously demonstrated that the proto-oncogene TCL1 is an Akt kinase coactivator. TCL1 binds to Akt and m...

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Autores principales: Künstle, Gerald, Laine, Jarmo, Pierron, Gaelle, Kagami, Shin-ichiro, Nakajima, Hiroshi, Hoh, Francois, Roumestand, Christian, Stern, Marc-Henri, Noguchi, Masayuki
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society for Microbiology 2002
Materias:
Cell Growth and Development
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC134690/
https://ncbi.nlm.nih.gov/pubmed/11839817
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