Caricamento...
Tissue Transglutaminase Serves as an Inhibitor of Apoptosis by Cross-Linking Caspase 3 in Thapsigargin-Treated Cells
Thapsigargin (THG) is an inhibitor of the endoplasmic reticulum Ca(2+)-ATPase that induces caspase 3 activation and apoptosis in HCT116 cells through a Bax-dependent pathway. In Bax-deficient HCT116 cells, however, THG specifically generates two additional species of caspase 3, termed p40 and p64, w...
Salvato in:
Autori principali: | , |
---|---|
Natura: | Artigo |
Lingua: | Inglês |
Pubblicazione: |
American Society for Microbiology
2006
|
Soggetti: | |
Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1346894/ https://ncbi.nlm.nih.gov/pubmed/16382148 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.26.2.569-579.2006 |
Tags: |
Aggiungi Tag
Nessun Tag, puoi essere il primo ad aggiungerne! !
|