ATP Hydrolysis and AMP Kinase Activities of Nonstructural Protein 2C of Human Parechovirus 1

The highly conserved picornavirus 2C proteins, thought to be involved in genome replication, contain three motifs found in NTPases/helicases of superfamily III. We report that human parechovirus 1 2C displays Mg(2+)-dependent ATP diphosphohydrolase activity in vitro, whereas other nucleoside triphos...

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Detalhes bibliográficos
Main Authors: Samuilova, Olga, Krogerus, Camilla, Fabrichniy, Igor, Hyypiä, Timo
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2006
Assuntos:
Genome Replication and Regulation of Viral Gene Expression
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1346857/
https://ncbi.nlm.nih.gov/pubmed/16379008
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.80.2.1053-1058.2006
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