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Evolution of Broad Host Range in Retroviruses Leads to Cell Death Mediated by Highly Cytopathic Variants

The ability of many retroviruses to cause disease can be correlated to their cytopathic effect (CPE) in tissue culture characterized by an acute period of cell death and viral DNA accumulation. Here, we show that mutants of a subgroup B avian retrovirus (Alpharetrovirus) cause a very dramatic CPE in...

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書誌詳細
主要な著者: Rainey, G. Jonah A., Coffin, John M.
フォーマット: Artigo
言語:Inglês
出版事項: American Society for Microbiology 2006
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC1346834/
https://ncbi.nlm.nih.gov/pubmed/16378958
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.80.2.562-570.2006
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