Arginine or Nitrate Enhances Antibiotic Susceptibility of Pseudomonas aeruginosa in Biofilms

Arginine enhanced the killing of Pseudomonas aeruginosa by ciprofloxacin and tobramycin under anaerobic, but not aerobic, growth conditions. Arginine or nitrate also enhanced the killing by these antibiotics in mature biofilms, reducing viable cell counts by a factor of 10 to 100 beyond that achieve...

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Bibliographic Details
Main Authors: Borriello, Giorgia, Richards, Lee, Ehrlich, Garth D., Stewart, Philip S.
Format: Artigo
Language:Inglês
Published: American Society for Microbiology 2006
Subjects:
Experimental Therapeutics
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC1346784/
https://ncbi.nlm.nih.gov/pubmed/16377718
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.50.1.382-384.2006
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