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In Vivo and In Vitro Studies of Antibiotic Release from and Bacterial Growth Inhibition by Antibiotic-Impregnated Polymethylmethacrylate Hip Spacers

The antimicrobial properties and the elution characteristics of gentamicin-vancomycin-loaded hip spacers were studied in vivo and in vitro. Vancomycin elution was greater than gentamicin elution. The antibiotic concentrations in vivo were less than those in vitro. Not dependent on implantation durat...

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Detalhes bibliográficos
Main Authors: Kelm, Jens, Regitz, Thilo, Schmitt, Eduard, Jung, Werner, Anagnostakos, Konstantinos
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2006
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1346773/
https://ncbi.nlm.nih.gov/pubmed/16377705
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.50.1.332-335.2006
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