A PE Protein Expressed by Mycobacterium avium Is an Effective T-Cell Immunogen

Infection of mice with Mycobacterium avium or immunization with a novel PE gene expressed by M. avium (MaPE) showed that a dominant T-cell immune response was elicited. Immunization with an MaPE DNA vaccine protected mice against an aerosol challenge with Mycobacterium tuberculosis, suggesting that...

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Detalhes bibliográficos
Main Authors: Parra, Marcela, Cadieux, Nathalie, Pickett, Thames, Dheenadhayalan, Veerabadran, Brennan, Michael J.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2006
Assuntos:
Microbial Immunity and Vaccines
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1346660/
https://ncbi.nlm.nih.gov/pubmed/16369041
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.74.1.786-789.2006
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