Role of Intimin-Tir Interactions and the Tir-Cytoskeleton Coupling Protein in the Colonization of Calves and Lambs by Escherichia coli O157:H7

Intimin facilitates intestinal colonization by enterohemorrhagic Escherichia coli O157:H7; however, the importance of intimin binding to its translocated receptor (Tir) as opposed to cellular coreceptors is unknown. The intimin-Tir interaction is needed for optimal actin assembly under adherent bact...

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Main Authors: Vlisidou, Isabella, Dziva, Francis, La Ragione, Roberto M., Best, Angus, Garmendia, Junkal, Hawes, Pippa, Monaghan, Paul, Cawthraw, Shaun A., Frankel, Gad, Woodward, Martin J., Stevens, Mark P.
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology 2006
Fag:
Molecular Pathogenesis
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1346653/
https://ncbi.nlm.nih.gov/pubmed/16369035
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.74.1.758-764.2006
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