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Elucidating TOR Signaling and Rapamycin Action: Lessons from Saccharomyces cerevisiae
TOR (target of rapamycin) is a phosphatidylinositol kinase-related protein kinase that controls cell growth in response to nutrients. Rapamycin is an immunosuppressive and anticancer drug that acts by inhibiting TOR. The modes of action of TOR and rapamycin are remarkably conserved from S. cerevisia...
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| Main Authors: | , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society for Microbiology
2002
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| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC134654/ https://ncbi.nlm.nih.gov/pubmed/12456783 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MMBR.66.4.579-591.2002 |
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