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Atypical Protein Kinase Cs Are the Ras Effectors That Mediate Repression of Myogenic Satellite Cell Differentiation

Oncogenic Ha-Ras is a potent inhibitor of skeletal muscle cell differentiation, yet the Ras effector mediating this process remains unidentified. Here we demonstrate that the atypical protein kinases (aPKCs; λ and/or ζ) are downstream Ras effectors responsible for Ras-dependent inhibition of myogeni...

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Detalhes bibliográficos
Main Authors: Fedorov, Yuri V., Jones, Nathan C., Olwin, Bradley B.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2002
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC134628/
https://ncbi.nlm.nih.gov/pubmed/11809805
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.22.4.1140-1149.2002
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