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Actin Is Required for Endocytosis at the Apical Surface of Madin-Darby Canine Kidney Cells where ARF6 and Clathrin Regulate the Actin Cytoskeleton

In epithelial cell lines, apical but not basolateral clathrin-mediated endocytosis has been shown to be affected by actin-disrupting drugs. Using electron and fluorescence microscopy, as well as biochemical assays, we show that the amount of actin dedicated to endocytosis is limiting at the apical s...

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Autores principales: Hyman, Tehila, Shmuel, Miri, Altschuler, Yoram
Formato: Artigo
Lenguaje:Inglês
Publicado: The American Society for Cell Biology 2006
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC1345679/
https://ncbi.nlm.nih.gov/pubmed/16251360
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.E05-05-0420
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